Renal replacement therapy for patients with end stage renal disease (ESRD) is an expensive procedure that emerging countries cannot afford.

To embark upon kidney and cardiovascular diseases, the ISN GO Research Committee (formerly known as COMGAN) initiated an early detection and intervention program for emerging countries.

A dedicated center for data collection and surveillance, the ISN Kidney Diseases Data Center (KDDC) was established at Mario Negri Institute in Ranica, Italy.